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Arch Dermatol. 1992 May;128(5):657-60.

Following lentigo maligna may not prevent the development of life-threatening melanoma.

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1
Dermatology Unit, Alfred Hospital, Melbourne, Australia.

Abstract

BACKGROUND:

Management of lentigo maligna (Hutchinson's melanotic freckle, in situ lentigo maligna melanoma) by regular observation relies on the detection of invasive melanoma before it has developed significant life-threatening potential. Recent studies indicate that lentigo maligna melanoma does not have a better prognosis than other forms of melanoma.

OBSERVATIONS:

A case is reported of an amelanotic lentigo maligna that evolved from a macular lesion to a deeply invasive, amelanotic, lentigo maligna melanoma within 6 months. The melanoma was Clark level IV and measured 3.0 mm in maximum tumor thickness.

CONCLUSIONS:

Observation of lentigo maligna at 6-month intervals would not seem to be sufficiently reliable in detecting the development of invasive lentigo maligna melanoma before it becomes a life-threatening disease. Early surgical excision is the treatment of choice.

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PMID:
1575529
[Indexed for MEDLINE]
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