HIV-infection in Russia and its Armed Forces is a serious threat to the national health and country's safety. Study of peculiarities of disease spread in the military collectives and HIV-infection manifestation is an actual problem. HIV-infection is diagnosed during the latent stage in all categories of servicemen and characterized by unchanged function of cellular and humoral immunity. In most servicemen with HIV-infection the disease course has a form of co-infection with parenteral hepatitis B and C.