Format

Send to

Choose Destination
See comment in PubMed Commons below
Infection. 2005 Feb;33(1):9-12.

Prevalence of hepatitis C virus infection in different population groups in southern Italy.

Author information

1
Epidemiology Unit, National Cancer Institute, G. Pascale Foundation, Naples, Italy.

Erratum in

  • Infection. 2005 Apr;33(2):103. Sabbatici, M [corrected to Sabbatini, M].

Abstract

BACKGROUND:

A cross-sectional investigation was carried out between 2000 and 2002 to assess the prevalence of hepatitis C virus infection (HCV) in Naples, southern Italy.

PATIENTS AND METHODS:

Five groups of individuals were investigated, two at low risk and three at high risk for HCV infection. Blood sample sera were collected among 5,391 individuals (4,059 men and 1,332 women): 1,972 general practitioner (GP) patients and 781 employees of the National Cancer Institute (NCI) of Naples (low-risk groups); 524 male prisoners, 1,436 intravenous drug users (IDUs) and 678 hemodialysis patients (high-risk groups).

RESULTS:

Overall HCV seropositivity rates ranged from 6.4% among employees of the NCI to 37.4% among male prisoners. HCV infection tended to generally increase with age, but in IDUs and in male prisoners the upward trend leveled off at 50 years of age. As compared to GP patients, IDUs (both sexes) and male prisoners had a nearly 6-fold increased risk of HCV infection, while HCV was nearly 3-fold more common among hemodialysis patients. Employees of NCI were at reduced risk of HCV infection, particularly women (odds ratio = 0.3).

CONCLUSION:

The study findings confirmed the high risk for HCV infection in IDUs and identified other population groups in southern Italy that should be offered HCV screening and counselling given the severe implications of HCV infection on health.

PMID:
15750753
DOI:
10.1007/s15010-005-4036-1
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Springer
    Loading ...
    Support Center