Synthesis of new derivatives of 8-aryl-3-phenyl-6,7-dihydro-4H-imidazo[2, 1-c][1,2,4]triazin-4-one

Acta Pol Pharm. 2004 Sep-Oct;61(5):373-7.

Author

Krzysztof Sztanke¹

Affiliation

¹ Department of Synthesis and Chemical Technology of Pharmaceutical Substances, Faculty of Pharmacy, Medical University, 6 Staszica Str., 20-081 Lublin, Poland.

PMID: 15747694

Abstract

Cyclocondensation of 1-aryl-2-hydrazono-imidazolidínes with ethyl phenylglyoxylate furnished a novel derivatives of imidazo[2,1-c][1,2,4]triazine.

Publication types

Comparative Study

MeSH terms

Anti-Bacterial Agents / chemical synthesis*
Anti-Bacterial Agents / pharmacology
Antifungal Agents / chemical synthesis*
Antifungal Agents / pharmacology
Aspergillus / drug effects
Candida / drug effects
Gram-Negative Bacteria / drug effects
Gram-Positive Bacteria / drug effects
Imidazoles / chemical synthesis*
Imidazoles / pharmacology
Microbial Sensitivity Tests
Structure-Activity Relationship
Triazines / chemical synthesis*
Triazines / pharmacology

Substances

Anti-Bacterial Agents
Antifungal Agents
Imidazoles
Triazines