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Am J Obstet Gynecol. 2005 Mar;192(3):862-7.

Risk factors for neonatal mortality among extremely-low-birth-weight infants.

Author information

1
Department of Community Health, Saint Louis University School of Public Health, St. Louis, MO, USA.

Abstract

OBJECTIVE:

The purpose of this study was to examine characteristics associated with neonatal mortality among extremely low-birth-weight infants (< or = 1000 g).

STUDY DESIGN:

A population-based, case-control study using linked Missouri birth and death certificates from 1989 to 1997 was conducted. Cases (n = 835) were defined as extremely low-birth-weight infants that died within 28 days of birth. Controls (n = 907) were randomly selected from extremely low-birth-weight infants that were alive at 1 year and were frequency matched to subjects by birth year and birth weight.

RESULTS:

Infants born with severe congenital anomalies and at the youngest gestational ages were at greatest risk for neonatal mortality. Other significant risk factors included maternal age (< 18 and > 34 years), vaginal delivery, nontertiary hospital care, malpresentation, male gender, and small for gestational age. Black race and preeclampsia were protective against early death.

CONCLUSIONS:

The risk of neonatal mortality among extremely low-birth-weight infants was associated with several maternal, infant, and obstetric factors, some of which may be preventable.

PMID:
15746683
DOI:
10.1016/j.ajog.2004.07.029
[Indexed for MEDLINE]

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