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Radiologe. 2005 Feb;45(2):113-8, 120-3.

[One decade of functional imaging in schizophrenia research. From visualisation of basic information processing steps to molecular-genetic oriented imaging].

[Article in German]

Author information

  • 1NMR-Forschung in der Psychiatrie, Zentralinstitut für Seelische Gesundheit, Mannheim. tost@zi-mannheim.de

Abstract

Modern neuroimaging techniques such as magnetic resonance imaging (MRI) and positron emission tomography (PET) have contributed tremendously to our current understanding of psychiatric disorders in the context of functional, biochemical and microstructural alterations of the brain. Since the mid-nineties, functional MRI has provided major insights into the neurobiological correlates of signs and symptoms in schizophrenia. The current paper reviews important fMRI studies of the past decade in the domains of motor, visual, auditory, attentional and working memory function. Special emphasis is given to new methodological approaches, such as the visualisation of medication effects and the functional characterisation of risk genes.

PMID:
15742098
DOI:
10.1007/s00117-004-1154-1
[PubMed - indexed for MEDLINE]
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