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Cell Res. 2005 Feb;15(2):97-8.

SHEsis, a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphism loci.

Author information

1
Bio-X Life Science Research Center, Shanghai Jiao Tong University, Shanghai, China.

Abstract

In multiloci-based genetic association studies of complex diseases, a powerful and high efficient tool for analyses of linkage disequilibrium (LD) between markers, haplotype distributions and many chi-square/p values with a large number of samples has been sought for long. In order to achieve the goal of obtaining meaningful results directly from raw data, we developed a robust and user-friendly software platform with a series of tools for analysis in association study with high efficiency. The platform has been well evaluated by several sets of real data.

PMID:
15740637
DOI:
10.1038/sj.cr.7290272
[Indexed for MEDLINE]
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