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Mol Microbiol. 1992 Mar;6(6):715-22.

An amino-proximal domain required for the localization of FtsQ in the cytoplasmic membrane, and for its biological function in Escherichia coli.

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Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas, Madrid, Spain.


The location of FtsQ, an Escherichia coli protein essential for cell division, is, under physiological conditions, in the cytoplasmic membrane facing towards the periplasmic space. An amino-proximal hydrophobic domain is required for FtsQ to reach its location and for its activity in the cell. Overexpression of modified forms of FtsQ is deleterious for the cell.

[Indexed for MEDLINE]

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