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Proc Natl Acad Sci U S A. 2005 Mar 8;102(10):3863-8. Epub 2005 Feb 28.

Theta oscillations and sensorimotor performance.

Author information

1
Department of Psychology, Institute for Mind and Biology, University of Chicago, 940 East 57th Street, Chicago, IL 60637, USA. lkay@uchicago.edu

Abstract

Performance and cognitive effort in humans have recently been related to amplitude and multisite coherence of alpha (7-12 Hz) and theta (4-7 Hz) band electroencephalogram oscillations. I examined this phenomenon in rats by using theta band oscillations of the local field potential to signify sniffing as a sensorimotor process. Olfactory bulb (OB) theta oscillations are coherent with those in the dorsal hippocampus (HPC) during odor sniffing in a two-odor olfactory discrimination task. Coherence is restricted to the high-frequency theta band (6-12 Hz) associated with directed sniffing in the OB and type 1 theta in the HPC. Coherence and performance fluctuate on a time scale of several minutes. Coherence magnitude is positively correlated with performance in the two-odor condition but not in extended runs of single odor conditional-stimulus-positive trials. Simultaneous with enhanced OB-HPC theta band coherence during odor sniffing is a significant decrease in lateral entorhinal cortex (EC)-HPC and OB-EC coherence, suggesting that linkage of the olfactory and hippocampal theta rhythms is not through the synaptic relay from OB to HPC in the lateral EC. OB-HPC coupling at the sniffing frequency is proposed as a mechanism underlying olfactory sensorimotor effort as a cognitive process.

PMID:
15738424
PMCID:
PMC553293
DOI:
10.1073/pnas.0407920102
[Indexed for MEDLINE]
Free PMC Article

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