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Colloids Surf B Biointerfaces. 2005 Mar 25;41(2-3):79-81. Epub 2004 Dec 18.

The synergistic activity of antibiotics combined with eight traditional Chinese medicines against two different strains of Staphylococcus aureus.

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  • 1Key Laboratory of Biomechanics & Tissue Engineering (Chongqing University), Ministry of Education Bioengineering College of Chongqing University, Chongqing 400044, PR China.


The ethanolic extracts of eight traditional Chinese medicines and four antibiotics were investigated for their combined effects on the resistance of Staphylococcus aureus (S. aureus) in vitro. Methicillin resistant S. aureus, which was isolated from patient and a standard strain, were used. Our results showed that there are differences in the effects of many combinations used on the standard strain and resistant strain of S. aureus. The ethanolic extracts of Isatis tinctoria, Scutellaria baicalensis and Rheum palmatum can improve the antimicrobial activity of four antibiotics we used.

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