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Infect Immun. 2005 Mar;73(3):1847-51.

Bacterial and host factors implicated in nasal carriage of methicillin-resistant Staphylococcus aureus in mice.

Author information

1
Unité des Agents Antibactériens, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France.

Abstract

Nasal carriage is a major risk factor for Staphylococcus aureus infection, especially for methicillin-resistant strains (MRSA). Using a mouse model of nasal carriage, we have compared several S. aureus strains and demonstrated increased colonization levels by MRSA in cystic fibrosis transmembrane conductance regulator-deficient mice and Toll-like receptor 2 (TLR2)-deficient mice but not TLR4-deficient mice.

PMID:
15731086
PMCID:
PMC1064969
DOI:
10.1128/IAI.73.3.1847-1851.2005
[Indexed for MEDLINE]
Free PMC Article

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