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Antimicrob Agents Chemother. 2005 Mar;49(3):1190-3.

In vitro development of resistance to six and four fluoroquinolones in Mycoplasma pneumoniae and Mycoplasma hominis, respectively.

Author information

1
Laboratoire de Bactériologie, Université Victor Segalen Bordeaux 2, 146 rue Léo Saignat, 33076 Bordeaux Cedex, France.

Abstract

Selection of resistant mutants in sequential subcultures with increasing concentrations of six and four different fluoroquinolones was studied for one reference strain each of Mycoplasma pneumoniae and Mycoplasma hominis, respectively. All fluoroquinolones tested selected for resistance, with alterations affecting the quinolone resistance-determining regions of the four target topoisomerase genes.

PMID:
15728924
PMCID:
PMC549269
DOI:
10.1128/AAC.49.3.1190-1193.2005
[Indexed for MEDLINE]
Free PMC Article

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