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Chem Soc Rev. 2005 Mar;34(3):276-85. Epub 2005 Feb 8.

Stimuli responsive polymers for biomedical applications.

Author information

1
School of Pharmacy and Biomedical Sciences, University of Portsmouth, St. Michael's Building, White Swan Road, Portsmouth, UKPO1 2DT.

Abstract

Polymers that can respond to external stimuli are of great interest in medicine, especially as controlled drug release vehicles. In this critical review, we consider the types of stimulus response used in therapeutic applications and the main classes of responsive materials developed to date. Particular emphasis is placed on the wide-ranging possibilities for the biomedical use of these polymers, ranging from drug delivery systems and cell adhesion mediators to controllers of enzyme function and gene expression (134 references).

PMID:
15726163
DOI:
10.1039/b406727d
[Indexed for MEDLINE]

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