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Dermatitis. 2004 Sep;15(3):150-3.

Allergic contact dermatitis from isocyanates among sculptors.

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Department of Dermatology, University of Pennsylvania, Philadelphia, PA 19147, USA.


Allergic contact dermatitis from isocyanates is rare. We present the cases of two sculptors who developed a dermatitis from polyurethane sculpting materials. The patients reacted to diphenylmethane diisocyanate and isophorone diisocyanate. One of the patients had positive patch-test reactions to 1,6-hexamethylene diisocyanate and toluene diisocyanate as well. The patients also exhibited a sensitivity to diaminodiphenylmethane, an amine that has been reported in other cases of isocyanate sensitivity.

[Indexed for MEDLINE]

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