Send to

Choose Destination
J Dent Res. 2005 Mar;84(3):265-8.

The effect of a bi-annual professional application of APF foam on dental caries increment in primary teeth: 24-month clinical trial.

Author information

Department of Preventive Dentistry, School of Stomatology, Wuhan University, Luoyu Road 237, Wuhan City, China 430079.


The purpose of this study was to evaluate the effect of a bi-annual professional application of acidulated phosphate fluoride (APF) foam on caries increment in the primary dentition over a two-year period in the People's Republic of China. In a double-blind, cluster-randomized, placebo-controlled trial, 392 children aged 3-4 years from 15 classes were randomly assigned to two groups on a school class basis. The experimental group (8 classes) received a bi-annual APF foam application, and the control group (7 classes) received the placebo. The mean increment of dmfs in the experimental group was 24.2% lower than that in the control group (p < 0.05). The significant caries reduction was observed on approximal surfaces in the experimental group compared with the control group (p < 0.01), but there were no differences on occlusal surfaces (p > 0.05). A bi-annual professional application of APF foam was effective in reducing the increment of dental caries in the primary teeth.

Comment in

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Atypon
Loading ...
Support Center