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Curr Opin Neurobiol. 2005 Feb;15(1):73-80.

Cadherins and catenins in synapse development.

Author information

1
Department of Anatomy and Developmental Biology, University College London, Gower Street, London WC1E 6BT, United Kingdom. p.salinas@ucl.ac.uk

Abstract

Cadherin-catenin complexes have been well established as key regulators of cell adhesion. Recent work has elucidated a pivotal role for these molecules in synaptic assembly, remodelling and plasticity. Far from being mere adhesive scaffolds, cadherins might directly regulate cell signalling to modulate synaptic connectivity.

PMID:
15721747
DOI:
10.1016/j.conb.2005.01.001
[Indexed for MEDLINE]

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