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J Clin Gastroenterol. 2005 Mar;39(3):220-3.

Motility abnormalities in esophageal body in GERD: are they truly related to reflux?

Author information

1
Laboratorio de Motilidad, Servicio de Aparato Digestivo, Hospital del Bierzo, León, Spain. lgarcia@hbrz.sacyl.es

Abstract

BACKGROUND:

Esophageal motility abnormalities have been observed in patients with gastroesophageal reflux disease.

GOALS:

The aim of the present study was to determine if esophageal motor disorders in patients with a positive response to the omeprazole test are related to the existence of reflux or they are concomitant findings.

STUDY:

A 24-hour pH monitoring and a stationary manometry were performed on 128 patients: 49 of them had normal manometry, 31 hypotensive lower esophageal sphincter, 29 motor disorder in esophageal body, and 19 hypotensive lower esophageal sphincter and motor disorder in esophageal body.

RESULTS:

We found an association between the presence of abnormal reflux and motor disorder in esophageal body (chi test; P < 0.05). However, ineffective esophageal motility was the disorder most strongly related to reflux, whereas the hypercontractile disorders were not clearly attributed to it.

CONCLUSIONS:

Esophageal manometric abnormalities should be considered cautiously before considering a motor disorder as a consequence of abnormal reflux.

[Indexed for MEDLINE]

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