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J Endocrinol Invest. 2004 Jun;27(6):570-3.

Prostatic neuroendocrine tumor in multiple endocrine neoplasia Type 2B.

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1
Department of Endocrinology Hospital CHU, Caen, France. bsalmon@ch-aleucom.fr

Abstract

We report the unusual occurrence of a neuroendocrine prostatic tumor in two young males with multiple endocrine neoplasia (MEN) 2B. Immunohistochemistry of the tumor markers may help differentiate a primary neuroendocrine prostate tumor from the metastasis of a medullary thyroid carcinoma of poor prognosis. MEN 2B hallmarks (i.e. plasma thyrocalcitonin and urinary metanephrines) may be systematically investigated in neuroendocrine tumors of the prostate, and conversely prostate examination may be performed in the periodic screening of MEN 2B male patients.

PMID:
15717656
DOI:
10.1007/BF03347481
[Indexed for MEDLINE]
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