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Clin Infect Dis. 2005 Mar 1;40(5):756-9. Epub 2005 Feb 4.

Paradoxical response to antituberculous therapy in infliximab-treated patients with disseminated tuberculosis.

Author information

1
Service of Internal Medicine, Hospital Mutua de Terrassa, University of Barcelona, Barcelona, Spain.

Abstract

Six of 284 patients treated with infliximab developed active tuberculosis. Four (67%) of these patients had a paradoxical response to antituberculous therapy. Physicians should be aware of the increased risk of a paradoxical response in this population and should consider the use of corticosteroids when a paradoxical reaction is suspected.

PMID:
15714425
DOI:
10.1086/427941
[Indexed for MEDLINE]

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