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Clin Infect Dis. 2005 Mar 1;40(5):750-3. Epub 2005 Jan 28.

Occult hepatitis B virus infection in HIV-infected patients with isolated antibodies to hepatitis B core antigen: Aquitaine cohort, 2002-2003.

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Fédération de Maladies Infectieuses et Tropicales, Centre Hospitalier Universitaire (CHU), Hôpital Pellegrin, Bordeaux, France.


We prospectively assessed the prevalence of occult hepatitis B virus (HBV) infection by investigating HBV replication in 160 human immunodeficiency virus (HIV)-infected patients with isolated antibodies to hepatitis B core antigen. This prevalence was 0.6% (1 case/160 patients; 95% confidence interval, 0%-3.4%). A second serum sample was collected later from 52 of the patients. HBV DNA was once again undetectable in all patients, except for the sole patient who had previously been found to be HBV DNA positive.

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