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Curr Opin Chem Biol. 2005 Feb;9(1):82-7.

Protein localization studies in the age of 'Omics'.

Author information

1
Alliance for Cell Signaling, Microscopy Lab, Stanford University School of Medicine, 975 California Ave, Palo Alto, CA 94304, USA.

Abstract

As thousands of new genes are identified in genomics efforts, the rush is on to learn something about the functional roles of the proteins encoded by those genes. Clues to protein functions, activation states and protein-protein interactions have been revealed in focused studies of protein localization. With technical breakthroughs such as GFP protein tagging and recombinase cloning systems, large-scale screens of protein localization are now being undertaken.

PMID:
15701458
DOI:
10.1016/j.cbpa.2004.12.002
[Indexed for MEDLINE]

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