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Behav Res Ther. 2005 Apr;43(4):521-32.

Diathesis stress model for panic-related distress: a test in a Russian epidemiological sample.

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Department of Psychology, The University of Vermont, John Dewey Hall, 2 Colchester Avenue, Room 202, Burlington, VT 05405-0134, USA.


To investigate a cognitive diathesis-stress model, the present study evaluated the main and interactive effects of anxiety sensitivity (AS) and exposure to aversive conditions (past month) in predicting theoretically relevant panic vulnerability variables in an epidemiologically defined sample from Russia (N = 390). Consistent with expectation, findings suggested that the combination of high levels of exposure to aversive conditions and high AS physical concerns predicted panic attacks (past week) and agoraphobic avoidance above and beyond the variance accounted for by negative affect. These findings are discussed in relation to biopsychosocial theories of panic disorder, which emphasize the importance of both a cognitive diathesis and stress component in the pathogenesis of the disorder.

[Indexed for MEDLINE]

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