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Acta Neurol Scand. 2005 Mar;111(3):199-201.

Pisa syndrome in a cohort of Alzheimer's disease patients.

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National Centre of Epidemiology, National Institute of Health, Rome, Italy.


Three Alzheimer's disease patients with Pisa syndrome were presented. These patients were treated with cholinesterase inhibitors within a post-marketing surveillance study. The clinical and pharmacological histories of these patients suggest a relation between cholinesterase inhibitors and the pleurothotonus. The diffuse use of cholinesterase inhibitors in the treatment of dementia may cause an increasing number of Pisa syndrome cases.

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