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Liver Transpl. 2005 Jan;11(1):108-10.

Rapid recurrence of nonalcoholic fatty liver disease after transplantation in a child with hypopituitarism and hepatopulmonary syndrome.

Author information

1
Division of Gastroenterology, Department of Medicine, Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA. maureen.jonas@childrens.harvard.edu

Abstract

Nonalcoholic fatty liver disease (NAFLD) has been reported in adults with hypothalamic or pituitary dysfunction, and some have progressed to end stage liver disease requiring transplantation. We report a teenager who initially presented with hypoxia due to intrapulmonary shunting, found to have NAFLD and cirrhosis associated with a hypothalamic tumor and panhypopituitarism. The NAFLD recurred very quickly after a successful liver transplant. Hepatopulmonary syndrome may be more common in cirrhosis associated with pituitary dysfunction than in other types of cirrhosis.

PMID:
15690545
DOI:
10.1002/lt.20332
[Indexed for MEDLINE]
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