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Bioorg Med Chem Lett. 2005 Feb 15;15(4):1107-9.

Human immunodeficiency virus-reverse transcriptase inhibition and hepatitis C virus RNA-dependent RNA polymerase inhibition activities of fullerene derivatives.

Author information

1
Kyoritsu University of Pharmacy, Shibakoen 1-5-30, Minato-ku, Tokyo 105-8512, Japan. mashino-td@kyoritsu-ph.ac.jp

Abstract

We examined the human immunodeficiency virus-reverse transcriptase and hepatitis C virus RNA-dependent RNA polymerase inhibition activities of cationic, anionic, and amino acid-type fullerene derivatives. Among the fullerene derivatives, the amino acid-type fullerene derivative was the most efficient in human immunodeficiency virus-reverse transcriptase inhibition.

PMID:
15686922
DOI:
10.1016/j.bmcl.2004.12.030
[Indexed for MEDLINE]

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