Format

Send to

Choose Destination
See comment in PubMed Commons below
J Nat Prod. 2005 Jan;68(1):14-8.

Two new chymotrypsin inhibitors isolated from the Cyanobacterium Microcystis aeruginosa NIES-88.

Author information

1
Graduate School of Environmental Studies, Tohoku University, Aramaki, Aoba-ku, Sendai 980-8579, Japan.

Abstract

Micropeptins 88-N (1) and 88-Y (2), new 3-amino-6-hydroxy-2-piperidone (Ahp)-containing cyclic depsipeptides, were isolated from Microcystis aeruginosa NIES-88. The structures were elucidated by analyses of HRFABMS, 1D and 2D NMR spectra, and chemical degradation. Micropeptins 88-N and 88-Y inhibited chymotrypsin. The inhibitory activities were closely related to the amino acid residue that was attached to the amino group of Ahp.

PMID:
15679310
DOI:
10.1021/np0401361
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for American Chemical Society
    Loading ...
    Support Center