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J Clin Pathol. 2005 Feb;58(2):220-1.

Osseous metaplasia in a tubular adenoma of the colon.

Author information

1
Department of Histopathology, East Lancashire Hospitals, Burnley BB10 2PQ, UK. waldaraji@aol.com

Abstract

An 85 year old woman presented with a one month history of change in her bowel habits in the form of alternating diarrhoea and constipation. She also noted some rectal bleeding. Flexible sigmoidoscopy revealed a 1.5 cm polyp 30 cm from the anus. The polyp was removed during the sigmoidoscopy by electrocautery and sent for histological examination. The polyp was a tubular adenoma with mild dysplasia. The adenoma contained numerous foci of metaplastic bone. These consisted of irregular islands of mineralised osteoid bone rimmed by a layer of scattered osteoblasts. This is the first case of osseous metaplasia in a tubular adenoma of the colon to be reported.

PMID:
15677548
PMCID:
PMC1770563
DOI:
10.1136/jcp.2004.020685
[Indexed for MEDLINE]
Free PMC Article

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