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Acta Med Indones. 2004 Jan-Mar;36(1):36-41.

Impaired glucose tolerance, impaired fasting glycaemia and cardiovascular risk.

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Dr. Wahidin Sudirohusodo Hospital Diabetes and Lipid Center Division of Endocronology and Metabolism, Department of Medicine, School of Medicine Hasanuddin University, Makasar.


Type 2 Diabetes Mellitus tends to increase year by year and it has a high morbidity and mortality, especially among those who have macro-vascular complication(s) as cardiovascular disease. There are many prevention efforts that have been done, especially primary prevention i.e. prevention of Type 2 Diabetes Mellitus development. Impaired Glucose Tolerance (IGT) and Imparied Fasting Gycaemia (IFG) is regarded as a phase between individual with normal blood glucose and type 2 diabetes mellitus. Individual with Impaired Glucose Tolerance (IGT) has higher possibility to develop Diabetes Mellitus compared to Impaired Fasting Gycaemia (IFG). Likewise, it also has more important role to cause Cardio-Vascular Disease. IGT may develop Cardiovascular Disease similar to Diabetes Mellitus, hence either IGT or Type 2 Diabetes Mellitus is categorized as independent risk factor of Cardio-Vascular Disease development. If compared to IFG then frequency of IGT is more excessive in the population, so that 2 hrs blood glucose after 75 gram glucose load test should be done in blood glucose testing.

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