In vitro activity of telithromycin against viridans group streptococci and Streptococcus bovis isolated from blood: antimicrobial susceptibility patterns in different groups of species

Antimicrob Agents Chemother. 2005 Feb;49(2):820-3. doi: 10.1128/AAC.49.2.820-823.2005.

Abstract

The in vitro activities of penicillin, erythromycin, clindamycin, and telithromycin were determined against 155 viridans group streptococci (VGS) and 18 Streptococcus bovis blood isolates. Heterogeneity in the susceptibility patterns and macrolide resistance phenotypes and genotypes in the different groups of VGS was detected. We found seven telithromycin-resistant S. bovis isolates all harboring the erm(B) gene.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anti-Bacterial Agents / pharmacology*
  • Bacterial Proteins / genetics
  • Bacterial Proteins / metabolism
  • Cattle
  • Drug Resistance, Bacterial
  • Humans
  • Ketolides / pharmacology*
  • Membrane Proteins / metabolism
  • Methyltransferases / genetics
  • Microbial Sensitivity Tests
  • Phenotype
  • Species Specificity
  • Streptococcal Infections / microbiology
  • Streptococcus bovis / drug effects*
  • Viridans Streptococci / drug effects*

Substances

  • Anti-Bacterial Agents
  • Bacterial Proteins
  • Ketolides
  • MefA protein, Streptococcus
  • Membrane Proteins
  • Methyltransferases
  • ErmA protein, Bacteria
  • telithromycin