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Antimicrob Agents Chemother. 2005 Feb;49(2):801-3.

Cloning of a novel gene for quinolone resistance from a transferable plasmid in Shigella flexneri 2b.

Author information

1
Department of Microbiology, Aichi Prefectural Institute of Public Health, 7-6 Nagare, Tsujimachi, Kita-ku, Nagoya, Aichi 462-8576, Japan. mami_hata@pref.aichi.lg.jp

Abstract

A novel gene for quinolone resistance was cloned from a transferable plasmid carried by a clinical isolate of Shigella flexneri 2b that was resistant to fluoroquinolones. The plasmid conferred low-level resistance to quinolones on Escherichia coli HB101. The protein encoded by the gene showed 59% amino acid identity with Qnr.

PMID:
15673773
PMCID:
PMC547361
DOI:
10.1128/AAC.49.2.801-803.2005
[Indexed for MEDLINE]
Free PMC Article
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