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Neurology. 2005 Jan 25;64(2):380-2.

Proneness to psychological distress and risk of Alzheimer disease in a biracial community.

Author information

1
Rush Alzheimer's Disease Center, Rush University Medical Center, Armour Academic Center, 600 S. Paulina, Suite 1038, Chicago, IL 60612, USA. rwilson@rush.edu

Abstract

Persons without dementia residing in a biracial community completed a brief scale of proneness to psychological distress, and 1,064 were subsequently examined for incident Alzheimer disease (AD) 3 to 6 years later. In analyses controlling for selected demographic and clinical variables, persons prone to distress were 2.4 times more likely to develop AD than persons not distress prone. This effect was substantially stronger in white persons compared to African Americans.

[Indexed for MEDLINE]

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