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Curr Biol. 2005 Jan 26;15(2):R58-61.

Skin cancer: lights on genome lesions.

Author information

1
Department of Microbiology, Institute of Biomedical Sciences, São Paulo, SP, Brazil. kmlima@usp.br

Abstract

Sunlight generates skin damage mainly by inducing DNA lesions in epidermal cells. The recent development of transgenic mice expressing specific photolyases has identified cyclobutane pyrimidine dimers as the major player in ultraviolet-induced damage, including skin cancer.

PMID:
15668158
DOI:
10.1016/j.cub.2004.12.056
[Indexed for MEDLINE]
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