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Am J Obstet Gynecol. 1992 Apr;166(4):1214-8.

Progression of diabetic retinopathy in pregnancy: association with hypertension in pregnancy.

Author information

1
Department of Obstetrics and Gynecology, University of Cincinnati College of Medicine, OH 45267-0526.

Abstract

OBJECTIVE:

To test the hypothesis that women with insulin-dependent diabetes and chronic or pregnancy-induced hypertensive disorders are at increased risk for developing retinopathic complications during pregnancy.

STUDY DESIGN:

One hundred fifty-four women with insulin-dependent diabetes were prospectively followed in an intensive program of diabetes in pregnancy. Ophthalmologic evaluations were obtained through pregnancy and at 6 to 12 weeks post partum, and findings were graded by a standard scale. Association of retinopathic progression with risk factors was tested with chi 2 and multiple logistic regression analysis.

RESULTS:

Fifty-one women had progression of retinopathy during pregnancy; postpartum regression was observed in 13 women. Changes in glycemic control early in pregnancy, chronic hypertension, and pregnancy-induced hypertension were significantly associated with progression of retinopathy.

CONCLUSION:

Women with insulin-dependent diabetes who have hypertensive disorders in pregnancy are at increased risk for progression of retinopathy.

PMID:
1566772
DOI:
10.1016/s0002-9378(11)90608-5
[Indexed for MEDLINE]

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