Background and objectives: There exist contradictory reports about low-intensity laser light-stimulated cell proliferation. The purpose of this study was to determine the effect of wavelength on proliferation of cultured murine cells.
Study design/materials and methods: Proliferation of primary cell cultures was measured after irradiation with varying laser wavelengths.
Results: Fibroblasts proliferated faster than endothelial cells in response to laser irradiation. Maximum cell proliferation occurred with 665 and 675 nm light, whereas 810 nm light was inhibitory to fibroblasts.
Conclusions: These observations suggest that both wavelength and cell type influence the cell proliferation response to low-intensity laser irradiation.