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Lasers Surg Med. 2005 Jan;36(1):8-12.

Effect of wavelength on low-intensity laser irradiation-stimulated cell proliferation in vitro.

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1
University of Oklahoma College of Dentistry, Oklahoma City, Oklahoma 73104, USA.

Abstract

BACKGROUND AND OBJECTIVES:

There exist contradictory reports about low-intensity laser light-stimulated cell proliferation. The purpose of this study was to determine the effect of wavelength on proliferation of cultured murine cells.

STUDY DESIGN/MATERIALS AND METHODS:

Proliferation of primary cell cultures was measured after irradiation with varying laser wavelengths.

RESULTS:

Fibroblasts proliferated faster than endothelial cells in response to laser irradiation. Maximum cell proliferation occurred with 665 and 675 nm light, whereas 810 nm light was inhibitory to fibroblasts.

CONCLUSIONS:

These observations suggest that both wavelength and cell type influence the cell proliferation response to low-intensity laser irradiation.

PMID:
15662631
DOI:
10.1002/lsm.20117
[Indexed for MEDLINE]
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