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Clin Infect Dis. 2005 Jan 15;40(2):309-12. Epub 2004 Dec 21.

Resistance to dual nucleoside reverse-transcriptase inhibitors in children infected with HIV clade A/E.

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1
Queen Sirikit National Institute of Child Health.

Abstract

The prevalence of nucleoside reverse-transcriptase inhibitor (NRTI) mutations was determined among 95 human immunodeficiency virus-infected Thai children who were treated with dual nucleoside reverse-transcriptase inhibitors. Almost all children had resistance to at least 1 NRTI, and approximately half of the children had resistance to multiple NRTIs. Cross-resistance to stavudine and azidothymidine was universal.

PMID:
15655753
DOI:
10.1086/427026
[Indexed for MEDLINE]
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