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Genes Dev. 2005 Jan 15;19(2):189-95.

Not just another hole in the wall: understanding intercellular protein trafficking.

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1
Department of Biology, Duke University, Durham, NC 27708, USA.

Abstract

Development and differentiation of multicellular organisms requires cell-to-cell communication. In plants direct signaling and exchange of macromolecules between cells is possible through plasmodesmata. Recently direct exchange of membrane-bound vesicles and organelles has been demonstrated between animal cells through formation of cytoplasmic bridges (tunneling nanotubes) in vitro. Here we review recent developments in cell-to-cell trafficking of macromolecules in plants and animals.

PMID:
15655108
DOI:
10.1101/gad.1271005
[Indexed for MEDLINE]
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