Relation between effects of adenosine on brachial artery reactivity and perfusion pattern in patients with known or suspected coronary artery disease

Deval Mehta; Gurpreet Baweja; Rajesh Venkataraman; Gilbert J Zoghbi; Thein Htay; Jaekyeong Heo; Navin C Nanda; Ami E Iskandrian

doi:10.1016/j.amjcard.2004.08.100

Relation between effects of adenosine on brachial artery reactivity and perfusion pattern in patients with known or suspected coronary artery disease

Am J Cardiol. 2005 Jan 15;95(2):304-7. doi: 10.1016/j.amjcard.2004.08.100.

Authors

Deval Mehta¹, Gurpreet Baweja, Rajesh Venkataraman, Gilbert J Zoghbi, Thein Htay, Jaekyeong Heo, Navin C Nanda, Ami E Iskandrian

Affiliation

¹ Division of Cardiovascular Diseases, Department of Medicine, University of Alabama at Birmingham, 1900 University Boulevard, Birmingham, AL 35294, USA.

PMID: 15642579
DOI: 10.1016/j.amjcard.2004.08.100

Abstract

This study examined the changes in brachial artery diameter and flow velocity in response to intravenous adenosine and compared the results to cuff occlusion and single-photon emission computed tomographic (SPECT) images. The change in diameter was less with adenosine than with cuff occlusion. There was no correlation between the presence of abnormal SPECT images and the responses to adenosine or cuff occlusion in either diameter or flow velocity.

Publication types

Evaluation Study
Research Support, Non-U.S. Gov't

MeSH terms

Adenosine / administration & dosage
Adenosine / pharmacology*
Blood Flow Velocity
Brachial Artery / drug effects*
Brachial Artery / physiology*
Coronary Artery Disease / physiopathology*
Female
Humans
Infusions, Intravenous
Male
Middle Aged
Pulsatile Flow
Tomography, Emission-Computed, Single-Photon
Vasodilator Agents / administration & dosage
Vasodilator Agents / pharmacology*

Substances

Vasodilator Agents
Adenosine