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Verapamil and valproic acid treatment of prolonged mania.

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  • 1Columbia University College of Physicians and Surgeons.


The case of an adolescent with severe mental retardation, blindness, and a complex of behavioral symptoms consistent with mania is reported. Symptoms include an increased activity level, mood liability, irritability, hyposomia, and severe self-injurious behavior. The successful use of verapamil and valproic acid in the treatment of prolonged mania in this child is described.

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