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Res Microbiol. 2005 Jan-Feb;156(1):1-6.

Bacterial conjugation: a potential tool for genomic engineering.

Author information

1
Departamento de BiologĂ­a Molecular, Universidad de Cantabria, C. Herrera Oria s/n, 39011 Santander, Spain. llosam@unican.es

Abstract

Bacterial conjugation is a mechanism for horizontal DNA transfer with potential for universal DNA delivery. The conjugal machinery can be separated into three functional modules: the relaxosome, the coupling protein, and a type IV protein secretion system. Module interchangeability among different conjugative systems opens up the possibility of "a la carte" engineering of DNA delivery into virtually any cell type.

PMID:
15636742
DOI:
10.1016/j.resmic.2004.07.008
[Indexed for MEDLINE]

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