[Cycloferon--a new domestic preparation for the prophylaxis of influenza and other acute respiratory viral infections]

F I Ershov; A L Kovalenko; T I Garashchenko; E P Sel'kova; V V Botvin'eva; A N Zhekalov; S V Petlenko; Iu K Bol'bot; M G Romantsov

[Cycloferon--a new domestic preparation for the prophylaxis of influenza and other acute respiratory viral infections]

Zh Mikrobiol Epidemiol Immunobiol. 2004 Nov-Dec:(6):47-51.

[Article in Russian]

Authors

F I Ershov, A L Kovalenko, T I Garashchenko, E P Sel'kova, V V Botvin'eva, A N Zhekalov, S V Petlenko, Iu K Bol'bot, M G Romantsov

PMID: 15636140

Abstract

The results of the placebo-controlled multicenter study of the epidemiological efficiency of the preparation Cycloferon for the prophylaxis of acute respiratory viral infections in children and adolescents are presented. A total of 16,000 children and adolescents were selected for the study. The epidemiological efficiency of the preparation manifested in 1.5- 2.9-fold decreased morbidity level with a protection index equal to 41 - 90%, was demonstrated.

Publication types

Clinical Trial
Multicenter Study
Randomized Controlled Trial

MeSH terms

Acridines / administration & dosage
Acridines / therapeutic use*
Administration, Oral
Adolescent
Child
Humans
Influenza, Human / prevention & control
Interferon Inducers / administration & dosage
Interferon Inducers / therapeutic use*
Respiratory Tract Infections / prevention & control*
Russia
Ukraine
Virus Diseases / prevention & control*

Substances

Acridines
Interferon Inducers
10-carboxymethyl-9-acridanone