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AIDS. 2005 Jan 3;19(1):93-5.

Antiretroviral therapy with tenofovir is associated with mild renal dysfunction.

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1
Center for HIV and Hepatogastroenterology, Duesseldorf, Germany.

Abstract

A cross-sectional study was conducted to compare patients treated with tenofovir with patients never treated with tenofovir. Patients on tenofovir showed a lower mean glomerular filtration rate estimated by creatinine clearance or cystatin C clearance compared with control patients. In total, 24 patients on tenofovir versus five control patients had proteinuria greater than 130 mg/day. In the majority of patients on tenofovir proteinuria was of tubular origin.

PMID:
15627039
[Indexed for MEDLINE]
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