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Biol Cybern. 1992;66(5):381-7.

Reduction of conductance-based neuron models.

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Department of Biology, Brandeis University, Waltham, MA 02254.


We present a scheme for systematically reducing the number of differential equations required for biophysically realistic neuron models. The techniques are general, are designed to be applicable to a large set of such models and retain in the reduced system as high a degree of fidelity to the original system as possible. As examples, we provide reductions of the Hodgkin-Huxley system and the A-current model of Connor et al. (1977).

[Indexed for MEDLINE]

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