Treatment of Nevus comedonicus with topical tazarotene and calcipotriene

J Drugs Dermatol. 2004 Nov-Dec;3(6):674-6.

Abstract

Nevus comedonicus is a rare developmental defect of the pilosebaceous unit. It is also thought to be a variant of epidermal nevus. Previously reported treatments include surgical excision, CO2 laser, dermabrasion, extraction, topical retinoic acid, and numerous topical keratolytics. We present a case of a 7-year-old boy with bilateral nevus comedonicus who experienced cosmetic improvement with topical tazarotene and calcipotriene cream. This combination represents a novel therapeutic approach to the treatment of this cutaneous abnormality.

Publication types

  • Case Reports

MeSH terms

  • Administration, Cutaneous
  • Calcitriol / administration & dosage
  • Calcitriol / analogs & derivatives*
  • Child
  • Dermatologic Agents / administration & dosage
  • Diagnosis, Differential
  • Drug Therapy, Combination
  • Facial Dermatoses / diagnosis
  • Facial Dermatoses / drug therapy*
  • Facial Dermatoses / pathology
  • Humans
  • Male
  • Nevus, Pigmented / diagnosis
  • Nevus, Pigmented / drug therapy*
  • Nevus, Pigmented / pathology
  • Nicotinic Acids / administration & dosage
  • Sweat Gland Neoplasms / diagnosis
  • Sweat Gland Neoplasms / drug therapy*
  • Sweat Gland Neoplasms / pathology

Substances

  • Dermatologic Agents
  • Nicotinic Acids
  • calcipotriene
  • tazarotene
  • Calcitriol