Updated classification of hemangiomas and other vascular anomalies

Lymphat Res Biol. 2003;1(4):259-65. doi: 10.1089/153968503322758067.

Abstract

Vascular anomalies comprise a widely heterogenous group of tumors and malformations. Great confusion has arisen because of the term hemangioma has been and is continued to be used to represent a multitude of vascular entities. This review presents the updated classification of vascular anomalies with the goal of clarifying the term hemangioma. In addition, newer clinical concepts in hemangiomas and other vascular tumors is presented. Hemangioma subtypes and hemangioma variants are also discussed, and a brief review of pyogenic granuloma and Kaposiform hemangioendothelioma is provided. Finally, the immunohistochemical marker GLUT1 is reviewed, a marker that heralds a new era in vascular anomalies research.

Publication types

  • Review

MeSH terms

  • Cardiovascular Abnormalities / classification
  • Cardiovascular Abnormalities / diagnosis*
  • Diagnosis, Differential
  • Endothelium, Vascular / pathology*
  • Female
  • Glucose Transporter Type 1
  • Granuloma, Pyogenic / diagnosis
  • Hemangioendothelioma / diagnosis
  • Hemangioma / classification
  • Hemangioma / diagnosis*
  • Hemangioma / pathology
  • Humans
  • Immunohistochemistry
  • Infant
  • Infant, Newborn
  • Male
  • Monosaccharide Transport Proteins / biosynthesis
  • Vascular Neoplasms / classification
  • Vascular Neoplasms / diagnosis

Substances

  • Glucose Transporter Type 1
  • Monosaccharide Transport Proteins
  • SLC2A1 protein, human