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Carbohydr Res. 2005 Jan 17;340(1):91-6.

The teichoic acid (C-polysaccharide) synthesized by Streptococcus pneumoniae serotype 5 has a specific structure.

Author information

1
Aventis Pasteur, Campus Mérieux, Biochemistry Research Department, 1541 Avenue Marcel Mérieux, F-69280 Marcy l' Etoile, France.

Abstract

The teichoic acid synthesized by Streptococcus pneumoniae serotype 5, also known as pneumococcal common antigen (C-polysaccharide), was purified. On the basis of compositional analysis, HPAEC-PAD analysis, MALDI-TOF mass spectrometry and NMR spectroscopy, made on the native polysaccharide and on the dephosphorylated repeating unit, the following structure is proposed: [structure: see text]. This C-polysaccharide (C-PS), differs from those previously described by the replacement of Glc by Gal in its repeating unit structure.

PMID:
15620671
DOI:
10.1016/j.carres.2004.10.021
[Indexed for MEDLINE]

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