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Curr Biol. 2004 Dec 29;14(24):R1064-77.

Mechanisms of protein import and routing in chloroplasts.

Author information

1
Department of Biology, University of Leicester, Leicester LE1 7RH, UK. rpj3@lec.ac.uk

Abstract

The vast majority of the approximately 3000 different proteins required to build a fully functional chloroplast are encoded by the nuclear genome and translated on cytosolic ribosomes. As chloroplasts are each surrounded by a double-membrane system, or envelope, sophisticated mechanisms are necessary to mediate the import of these nucleus-encoded proteins into chloroplasts. Once inside the organelle, many chloroplast proteins engage one of four additional protein sorting mechanisms that direct targeting to the internal thylakoid membrane system.

PMID:
15620643
DOI:
10.1016/j.cub.2004.11.049
[Indexed for MEDLINE]
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