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Cell. 2004 Dec 29;119(7):907-10.

Molecular mechanisms of muscle atrophy.

Author information

1
Ottawa Health Research Institute, 501 Smyth Road, Ottawa, Ontario K1H 8L6, Canada.

Abstract

Skeletal muscle atrophy has extreme adverse consequences. Molecular mechanisms that mediate the process of atrophy are not well defined. Recent studies have focused on diverse molecular cascades that control the activation of ubiquitin ligases, indicating that the involvement of the ubiquitin proteasome may be common to a range of atrophic stimuli.

PMID:
15620349
DOI:
10.1016/j.cell.2004.12.007
[Indexed for MEDLINE]
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