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Anesthesiology. 2005 Jan;102(1):63-8.

Electronic nose prediction of a clinical pneumonia score: biosensors and microbes.

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Department of Anesthesia, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.



The authors performed a prospective study to determine whether breath test analysis using an electronic nose correlates with a clinical pneumonia score.


Exhaled gas was sampled from the expiratory limb of the ventilator in mechanically ventilated surgical intensive care patients and assayed with the electronic nose. Components of a clinical pneumonia score were recorded concurrently.


The score predicted by the electronic nose showed good correlation with the actual pneumonia score (r = 0.81). Bland Altman analysis showed a mean bias of 0.0 (limits +/- 2.6).


The electronic nose is a new biosensor technology that correlates with a clinical pneumonia score.

[Indexed for MEDLINE]

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