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Med Hypotheses. 2005;64(3):572-4.

Lesser anterior chamber dimensions in women may be a predisposing factor for malignant glaucoma.

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  • 1Department of Ophthalmology, Khalili Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.


Malignant glaucoma is a potentially devastating complication of intraocular surgery that may also occur spontaneously. In this condition the aqueous is diverted into the vitreous, so the Iris lens diaphragm is moved forward. This causes shall owing of the anterior chamber and increasing of intraocular pressure. By reviewing 103 patients with malignant glaucoma, the disease was more prevalent in women that men (70% vs 30%). Anterior chamber dimensions in the women is 4% lesser than the men. Therefore, it is hypothesized that these may be due to more anterior position of the lens which not only causes lesser dimension of the anterior chamber but also more cilio-lenticular block and further aqueous diversion into the vitreous cavity, in the women.

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