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Cell Microbiol. 2005 Jan;7(1):1-9.

In vivo induced antigen technology (IVIAT).

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  • 1Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA, USA.


In vivo induced antigen technology (IVIAT) is a technique that identifies pathogen antigens that are immunogenic and expressed in vivo during human infection. IVIAT is complementary to other techniques that identify genes and their products expressed in vivo. Genes and gene pathways identified by IVIAT may play a role in virulence or pathogenesis during human infection, and may be appropriate for inclusion in therapeutic, vaccine or diagnostic applications.

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